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Ahmeid, Mutaz Sabah
- Estimation the Level of Follicular Fluid Follistatin in Women Undergoing Intracytoplasmic Sperm Injection
Abstract Views :281 |
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Authors
Affiliations
1 Kirkuk health directorate, Kirkuk city, IQ
2 M.B.Ch.B, M.Sc, Ph.D in Clinical Biochemistry, College of Medicine, Tikrit University, IQ
3 Ph.D in immunology, Middle Technical University-College of Medical & Health Technology-Baghdad, IQ
4 B.Sc, M.Sc in Chemistry, Department of Biochemistry, College of Medicine, Tikrit University, IQ
1 Kirkuk health directorate, Kirkuk city, IQ
2 M.B.Ch.B, M.Sc, Ph.D in Clinical Biochemistry, College of Medicine, Tikrit University, IQ
3 Ph.D in immunology, Middle Technical University-College of Medical & Health Technology-Baghdad, IQ
4 B.Sc, M.Sc in Chemistry, Department of Biochemistry, College of Medicine, Tikrit University, IQ
Source
Medico-Legal Update, Vol 20, No 1 (2020), Pagination: 1360-1365Abstract
Objectives: A prospective study carried out in Kirkuk city from 15th of January 2019 to 10th of April 2019, included 45 women who were enrolled in assisted reproductive technology (ART) programs in infertility Centre/Kirkuk, Iraq. Patients and Method: All women were subjected to the basic fertility work-up at the infertility center which consists of history taking,physical examination, ovulation detection, evaluation of tubal patency and uterine cavity. The average age of the included women ranged between 20 and 42 years old. All women were enrolled in short protocol type of IVF/ICSI cycle and they had normal menstrual cycles. Nearly 5 ml of follicular fluid was obtained from all women undergoing ICSI for estimation of follistatin level by ELISA technique. Results: The present study showed that 31.1% (14 of 45) of women underwent ISCI technique became pregnant and 68.9% were non-pregnant (31 of 45). The highest mean of age were recorded among pregnant women compared with non-pregnant women (32.21 ± 6.68 v.s. 31.80 ± 5.38 year) although the result was non-significant (P: > 0.05). The highest mean of BMI were recorded among non-pregnant women compared with pregnant women (23.92 ± 1.55 v.s 25.36 ± 1.99 kg/m2), the result was significant. The highest mean level of follicular fluid follistatin evaluated in pregnant compared with non pregnant (10.20 ± 0.30 v.s 9.83 ± 0.58 ng/ml) although the result was high significant difference (p: < 0.05). The study showed that there was negative correlation of follicular fluid follistatin level with age in pregnant women (r= -0.3), with positive correlation of with age in non-pregnant women. Conclusions: There was a highly significant relation of follicular fluid follistatin with pregnancy outcomes after ICSI.Keywords
Follistatin, Follicular Fluid, ICSI, Infertility, Pregnancy.- Serum α-Klotho Level in the Patients Subjected to Hemodialysis in Association with Lipid Profile
Abstract Views :279 |
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Authors
Affiliations
1 Kirkuk Health Directorate, Kirkuk City, IQ
2 M.B.Ch.B, M.Sc, Ph.D in Clinical Biochemistry, College of Medicine, Tikrit University, IQ
3 Ph.D in Immunology, Middle Technical University, College of Medical & Health Technology, Baghdad, IQ
4 B.Sc, M.Sc in Chemistry, Department of Biochemistry, College of Medicine, Tikrit University, IQ
1 Kirkuk Health Directorate, Kirkuk City, IQ
2 M.B.Ch.B, M.Sc, Ph.D in Clinical Biochemistry, College of Medicine, Tikrit University, IQ
3 Ph.D in Immunology, Middle Technical University, College of Medical & Health Technology, Baghdad, IQ
4 B.Sc, M.Sc in Chemistry, Department of Biochemistry, College of Medicine, Tikrit University, IQ
Source
Medico-Legal Update, Vol 20, No 1 (2020), Pagination: 1366-1372Abstract
Background: Klotho, is a protein associated with life extension plays a important role in kidney disease progression, anti-aging, anti-oxidation, modulation of ion transport, and development of disturbed mineral metabolism. The aim of the study was to measure Soluble α-Klotho(SAKL) levels in chronic kidney disease(CKD) patients before and after dialysis in relation with Lipid profile. Methods: This shortprospective hospital-based study was done in the Department of Chemistry and Biochemistry, College of medicine, Tikrit University, Tikrit, Iraq. The study was carried out for 30 patients subjected to Hemodialysis recruited from Tikrit Teaching Hospital, hemodialysis unit between 1st December, 2018 and 1st April, 2019. The study also included 30 adult persons looks healthy with no prior medical or family history of CKD as a control participated in this study. The levels of SAKL and lipid profile were measured in the serum of 30 patients, before and after Hemodialysis and compared with controls. Results: The study revealed increased in the SAKL level in CKD patients before dialysis compared to healthy control group, and decreased in group of CKD after dialysis compared to control group. Furthermore, there was a significant positive correlation of SAKL level with serum Triglyceride and Very low density lipoprotein cholesterol(VLDL-C) in CKD patients before dialysis. Conclusions: There was a highly significant relation of SAKL with lipid abnormality in CKD patients under hemodialysis.Keywords
Soluble α,-Klotho, Chronic Kidney Disease, Hemodialysis, Lipid Profile.- Evaluation the Serum Level of Melatonin in Iraqi Patients with Polycystic Ovarian Syndrome
Abstract Views :315 |
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Authors
Affiliations
1 Obstetrics and Gynecology of Alzahra’a Hospital, Almosyab City, IQ
2 M.B.Ch.B., M.Sc., Ph.D. in Clinical Biochemistry, College of Medicine, Tikrit University, IQ
1 Obstetrics and Gynecology of Alzahra’a Hospital, Almosyab City, IQ
2 M.B.Ch.B., M.Sc., Ph.D. in Clinical Biochemistry, College of Medicine, Tikrit University, IQ